• The current study has investigated the cell death pathway

  2018-11-06

  

  The current study has investigated the cell death pathway(s) utilized by mESCs in response to etoposide (ETO), a topoisomerase II poison that indirectly induces DNA double strand breaks (DSBs) (Baldwin and Osheroff, 2005). The data show that ETO not only induces cell death with hallmarks of both PCD

• Introduction Osteoprogenitor cells are ubiquitous multipoten

  2018-11-06

  

  Introduction Osteoprogenitor cells are ubiquitous, multipotent stromal cells capable of differentiating into multiple cellular lineages [e.g. osteoblasts (responsible for secretion of the extracellular bone matrix) and osteocytes (mature bone cells)], and replenish existing local cell populations (

• The dedifferentiation of lineage committed cells into

  2018-11-06

  

  The dedifferentiation of lineage-committed GSK126 into more primitive stem-like states during transplantation is similar to the cell-state transitions that occur during tumor initiation (Keller et al., 2010). For example, preceding the onset of basal cell carcinoma, adult tumor-initiating cells are

• LY 2109761 Our findings directly interface with the

  2018-11-05

  

  Our findings directly interface with the role of CXCL12 (SDF1)/CXCR4 signaling in adult HSPC migration: CXCL12 levels increase in response to stress and inflammation, and influence HSPC mobilization and extravasation within the adult BM (Dar et al., 2006). As hematopoietic niches are hypoxic during

• This however does not take place An insignificant decrease i

  2018-11-05

  

  This, however, does not take place. An insignificant decrease in the and ΔEv values in n-PbS : O+ compared to the data for the initial sample is within the margin of experimental error and could be regarded merely as a tendency in value decrease of the energy parameters discussed when passing from p

• br Convergence study and computational results To

  2018-11-05

  

  Convergence study and computational results To adequately choose the size of the finite elements and the integration step, we examined the convergence of the results as a function of these parameters. Given the physical nature of the simulated vibration process, the grid dimension and the integra

• UNC0379 br If the quality of vibration suppression

  2018-11-05

  

  If the quality of vibration suppression in the beam proves unsatisfactory, it is necessary to return to identification experiments and additionally determine the subsequent rows of the eigenmode matrices. Next, it is necessary to recalculate the modal matrices according to formula (7) and use them

• Given that residuals are likely to display non zero within

  2018-11-05

  

  Given that residuals are likely to display non-zero within-group correlations despite the regional fixed effects (Bertrand, Duflo, & Mullainathan, 2004), all standard errors were clustered at the catchment area (primary health care unit) level. Results Table 1 shows average sample characteristic

• Broader understanding of pathways of

  2018-11-05

  

  Broader understanding of pathways of influence could also inform intervention development. A walking intervention involving the installation of walking route signage and leadership for local walking groups in two low-income neighbourhoods in Ireland had only a marginal effect on physical activity (B

• If mother liquor L is supplied

  2018-11-05

  

  If mother liquor L is supplied to evaporator E without preheating, that is at t = t = 0 °C, consumption of heat in the evaporator is high and the beta lactamase ratio of the compressor reaches very high values of n = 40–45 (Fig. 7a). Failure to preheat mother liquor leads to a significant increase i

• br Geological setting and sample characteristics From

  2018-11-05

  

  Geological setting and sample characteristics From South to North, the Tibetan Plateau mainly comprises the Himalaya, Lhasa, Qiangtang, and Songpan-Ganzi Blocks (Yin and Harrison, 2000; Chung et al., 2005) (Fig. 1a). The Himalayan Block lies between the Indian shield to the south and the Indus-Ya

• Our study has several limitations This pilot study was unbli

  2018-11-05

  

  Our study has several limitations. This pilot study was unblinded without a control group. We cannot discern if the positive effect is a result of the urologist interviews or the patient\'s own expectations to stem cell therapy or if in fact the stem norepinephrine bitartrate themselves by differen

• It is unclear whether the adipose derived progenitor cells

  2018-11-05

  

  It is unclear whether the adipose-derived progenitor tyrosine kinase receptor exert a role in the beneficial effect of the AGTP. Recent data suggested that cardiac adipose-derived progenitors have an inherent cardiac-like phenotype and may support heart homeostasis, perhaps as a cell reservoir for

• br Introduction Prostate cancer strikes one in six

  2018-11-05

  

  Introduction Prostate cancer strikes one in six men and is the second leading cause of cancer-related deaths in men after lung cancer in the United States. Prostate cancer arises mainly from prostatic intraepithelial neoplasia (PIN), a precursor lesion that ultimately progresses to adenocarcinoma

• Previous work showed that lncRNAs show higher tissue

  2018-11-05

  

  Previous work showed that lncRNAs show higher tissue specificity compared to mRNAs (). The work of Ching et al. supported this notion, and extended it by showing a reduction of specificity after malignant transformation, which is consistent with the de-differentiation status of cancers widely observ

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